🐾 Liver Disease in Dogs and Cats
Sometimes our dogs and cats are diagnosed with liver disease. When the liver isn’t working properly, pets often feel very unwell — tired, off their food, or just “not themselves.”
There are many different liver problems, and diagnosis can be challenging. The good news is that treatment is often rewarding, especially when disease is picked up early.
🧪 What Does the Liver Do?
The liver is a vital organ with many jobs:
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Produces and secretes bile to break down fats during digestion
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Processes and stores nutrients from food
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Stores vitamins and minerals
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Removes toxins and waste products from the blood
Because it is constantly processing substances, the liver is vulnerable to damage from toxins, infections, cancer, and other diseases. Damage can lead to inflammation (hepatitis).
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Early disease: the liver becomes swollen and enlarged
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Progressive disease: healthy liver tissue is replaced by scar tissue
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Severe disease: once 70–80% of the liver is damaged, changes are irreversible
⚠️ Causes of Liver Disease
Liver disease can develop from many factors:
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Infections – bacterial, viral, or parasitic
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Toxins or drugs – such as pesticides, antifreeze, or certain medications
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Endocrine disorders – diabetes, Cushing’s disease, or hyperthyroidism
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Genetic predisposition – common in some breeds
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Cancer – primary liver cancer or spread from other sites
🐶🐱 Symptoms of Liver Disease
Signs can be vague, but may include:
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Vomiting or diarrhoea
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Drinking and urinating more than usual
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Loss of appetite
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Weight loss
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Behaviour changes, confusion, or seizures
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Jaundice (yellow gums, skin, or eyes)
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Smelly breath
🔍 Diagnosis
At Pittwater Animal Hospital, we use a range of diagnostics to assess the liver:
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Look for elevated liver enzymes
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Check albumin, a protein produced by the liver
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Bile acid test: compares blood samples before and after feeding to assess how well the liver “recycles” bile acids
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Assess concentration (kidneys and liver work closely together)
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Check for protein, infection, or abnormal cells
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X-rays: show size and shape of the liver and screen for abdominal changes
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Ultrasound: reveals nodules, masses, gall bladder issues, and surrounding organ health
Biopsy
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Provides the most definitive diagnosis, but is invasive and not always possible (especially if clotting is impaired).
💊 Treatment
Treatment depends on whether the disease is acute (sudden onset) or chronic (long-term).
Acute liver disease often needs intensive hospital care, including:
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IV fluids with electrolyte adjustment
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Antibiotics (if infection suspected)
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Nutritional support
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Medication for nausea or stomach irritation
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Careful monitoring of blood and urine
Chronic liver disease focuses on support and slowing progression:
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Diet changes to reduce workload on the liver
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Antioxidants and hepatoprotective supplements
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Lactulose to bind gut toxins
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Medications for nausea or discomfort
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Monitoring weight, appetite, and blood results
🛡️ Prevention
You can help reduce your pet’s risk of liver disease by:
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Keeping toxic substances (antifreeze, rodenticides, pesticides) away from pets
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Avoiding harmful foods such as chocolate, macadamia nuts, alcohol, and avocado
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Vaccinating dogs against infectious hepatitis and leptospirosis
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Maintaining a healthy diet and weight
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Scheduling regular check-ups with routine blood and urine testing
Routine tests at desexing, dental procedures, and senior checks allow us to track your pet’s liver values over time. Subtle changes can often be detected before your pet shows outward signs of illness.
❓ FAQs About Liver Disease
What does it mean if my cat or dog has liver disease?
It means their toxin removal and vitamin-producing system is compromised. This can cause chronic illness and, if untreated, death.
The good news is that liver disease can often be detected early through blood tests. Monitoring allows us to slow down progression, adjust diet, and manage symptoms before your pet becomes very unwell.
What if my cat or dog is sick with liver disease?
Unwell pets may have acute liver disease (sudden onset, best treated with intensive care) or advanced chronic disease (where options are more limited). Your vet will guide you through the best approach depending on the stage.
What is end-stage liver disease?
This is when most of the liver’s function has been lost. Signs include:
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Severe vomiting
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Increased drinking and urination
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Jaundice (yellow gums/eyes)
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Weight loss
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Smelly breath
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Possible seizures
Sadly, in pets we cannot offer liver transplants. Most reach a point where quality of life is poor.
What can I do if my cat or dog has end-stage liver disease?
End-stage disease causes severe suffering. Intensive hospital treatment may temporarily improve things, but decline is inevitable.
To avoid an unpleasant death, many owners choose euthanasia once their pet is no longer eating, is vomiting frequently, or begins to seizure.
Could I have prevented my pet’s liver disease?
Not always — some causes are genetic or unavoidable.
But:
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Treating infections, keeping teeth healthy, and feeding a balanced diet can reduce risk
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Early diagnosis through blood and urine tests helps catch problems before they’re advanced
When should my pet have screening tests?
We recommend:
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A baseline blood test at desexing
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Repeat tests before any anaesthetic
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Annual senior checks from 7 years in dogs and 10 years in cats
These allow us to spot changes early and adjust care accordingly.
Make an Appointment with the Vet →
Call us on 9913 7979
Or email reception@pittvets.au